Carbohydrate based resins for polymer assisted solution phase synthesis

Carbohydrate based beads can be derivatised to produce high loading resins which are comparable in both solvent compatibility and loading of required functionality to commercial polystyrene based resins, that are used in polymer assisted solution phase synthesis. The results from the application of a carbohydrate based resin to the acylation of amines and the bromination of alkenes and arenes are presented.